Mechanisms of Plasma Hemoglobin Clearance after Acute Hemolysis
نویسندگان
چکیده
منابع مشابه
Clearance and control mechanisms of hemoglobin from cradle to grave.
Hemoglobin is a highly reactive molecule, and besides its oxygen-carrying capacity, it has multiple enzymatic and ligand-binding activities that have only recently been explored as fundamental pathophysiologic mechanisms. Nitric oxide neutralization, generation of potentially toxic radical species, and heme-mediated inflammation are among the most extensively studied mechanisms of Hb-mediated p...
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In a preceding report (1) it was shown that those redox compounds that cause Heinz body anemias in vivo produce a sequence of changes in vitro in solutions of crystalline hemoglobin culminating in the precipitation of hemoglobin as spherical granules. These granules appear to be identical with Heinz bodies. The sequence of changes produced in hemoglobin by these compounds includes: 1) the forma...
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چکیده ندارد.
Peristaltic infusion of red blood cells: analysis of hemolysis ratio, plasma hemoglobin and potassium levels
Introduction It is unclear whether the use of linear peristaltic infusion pumps with different propulsion mechanisms can affect the quality of red blood cells (RBCs) transfusion. We hypothesized that the mechanism of liquid propulsion, infusion rate, complete or incomplete compression of the infusion sets segment and type of pumping segment composition materials are variables that can influence...
متن کاملThe clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease.
CONTEXT The efficient sequestration of hemoglobin by the red blood cell membrane and the presence of multiple hemoglobin clearance mechanisms suggest a critical need to prevent the buildup of this molecule in the plasma. A growing list of clinical manifestations attributed to hemoglobin release in a variety of acquired and iatrogenic hemolytic disorders suggests that hemolysis and hemoglobinemi...
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ژورنال
عنوان ژورنال: Annals of Surgery
سال: 1966
ISSN: 0003-4932
DOI: 10.1097/00000658-196604000-00004